#4 Louisville 39.1905 (10-14) | Game 1 02/24/2025 6:00 PM CT | #5 Palmyra 37.2857 (5-18) | |
| #1 Ashland-Greenwood 44.5714 (20-5) | Game 2 02/25/2025 5:30 PM CT | Louisville (77-46) | #3 Bishop Neumann 42.0000 (12-11) | Game 3 02/25/2025 7:00 PM CT | #2 Johnson County Central 42.8261 (16-9) |
| Ashland-Greenwood (59-38) | Game 4 02/27/2025 6:00 PM CT | Bishop Neumann (58-41) |
| | Ashland-Greenwood (37-36) | |
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